KRAS (G12C), Isoform A, His-Tag, GDP-Loaded Recombinant 100640 from BPS Bioscience, Inc.

Description

Human KRAS, also known as C-K-RAS, CFC2, and K-RAS2A, GenBank Accession No. NM_033360, a.a. 2-186 with G12C mutation and N-terminal His-tag, expressed in an E. coli expression system. MW=23 kDa. KRAS (G12C) His-Tag (BPS Bioscience #100413), is loaded with GDP. Unbound GDP was removed by spin column. Ready for use in the GDP/GTP exchange assay or as a negative control for KRAS-RAF interaction

Product Specs
ItemKRAS (G12C), Isoform A, His-Tag, GDP-Loaded Recombinant
CompanyBPS Bioscience, Inc.
Price Pricing Info Supplier Page View Company Product Page
Catalog Number100640
Quantity4 x 60 µg
Conjugate/TagN-terminal His-tag
Molecular Weight23 kDa
SpeciesHuman
Domain/Region/Terminus2-186
NCBI Full Gene NameKRAS proto-oncogene, GTPase
NCBI Gene AliasesOES, NS, KRAS1, KRAS2, KI-RAS, K-RAS4A, c-Ki-ras2, c-Ki-ras, K-RAS4B, RASK2, K-RAS2B, K-RAS2A, RALD, K-Ras 2, C-K-RAS, K-Ras, CFC2, NS3, 'C-K-RAS
TypeProtein
Format20 mM HEPES, pH 7.4, 150 mM NaCl, and 1 mM DTT
ApplicationsUseful for nucleotide exchange assay, KRAS(G12C) inhibitors screening, and selectivity profiling